YAKHAK HOEJI (약학회지)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Studies on the anti-inflammatory glycosides of panax ginseng

  • Han, Byung-Hoon (Natural Products Research Institute, Seoul National University) ;
  • Han, Yong-Nam (Natural Products Research Institute, Seoul National University) ;
  • Woo, Lin-Keun (Natural Products Research Institute, Seoul National University)
  • Published : 1972.09.01
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Abstract

Two anti-infalmmatory glycosides, Panax saponin A, $C_{47}H_{72}O_{14}$ center dot $2H_{2}O$, m.p. $208-10^{\circ}$ and C, m.p. $196-202^{\circ}$, were isolated from the methanol extract of Panax ginseng. The anti-inflammatory activity of Panax saponin A was found to have delayed and prolonged characteristics. The partial structure of Panax saponin A was established to be ${\beta}{\betha}$'20S-protopanaxatriol-diglucoside. One of glucose residues was bound to the 20S-hydroxyl group of aglycone.

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