Synthesis of 2,6-dichloro-4-Nitro Aniline Mercuric Acetate and Its Pharmaceutical Effects

2,6 dichloro-4-Nitro Aniline Mercuric Acetate의 合成과 그 藥劑效果에 관한 硏究

A large variety of weed killers, insecticides, and bactericiedes on the market today are of almost infinite variety, but their pharmacological effects are different from each other according to the objects to cope with. Therefore, it is hoped that some chemical substance which serves as weed killer, an insecticide, and a bactericede at a same time, should be synthesized, in order to save expense and labor. I anticipated that the desire would be met by introducing to a molecule the radical which has the three effects. Here, I made an attempt of introducing $Cl_2$ gas to aniline considering the following respects: 1. Introduction velocity of $Cl_2$ gas under the varied temeratures and velocities of $Cl_2$ gas 2. The effect of reaction period under the condition which gives the most satisfactory yield. 3. The actions of catalysts, $SbCl_3$, $FeCl_3$, and $MoCl_5$, and their proportions when a mixture of the three catalysts is used in producing 2,6-dichloro-aniline. After consideration of above phenomena, the maximum production rate of 79.5% of 2.6-compound was obtained. With the compound I synthesized 2.6-dichloro-4-nitroaniline-mercuric acetate. Investigations of the effects of the compound as weed killer, an insecticide, and a bactericide showed that the compound, 2,6-dichloro-4-Nitro Aniline mercuric acetate has a satisfactory herbi-insecti-bactericidal effect.