Tropane alkaloid를 확인하는 Vitali반응에 관한 연구

Die Vitali-Reaktion zur Erkennung der Tropa-Alkaloide

지금까지의 tropane-alkaloid의 확인방법으로는 tropic acid의 ester계인 atropine 등등의 화합물에서만 가능하였었고 mandelic acid계인 homatropine 등에는 불가능하였었으나 $D{\ddot{u}}nschichtplatte$를 통한 본실험에서는 그 어느것이든 Vitali 반응에서 오는 Violett 색을 증명할 수 있었고 Violett 색의 생성은 알칼리용액중에서 일어나는 carb-anion의 mesomeri화라고 단정한다.

The identification methods for tropane alkaloids so far known were limited on tropic acid esters such as atropine and was unable to detect mandelic acid esters such as homatropine. The present method employing thin-layer chromatography was able to detect violet coloration developed with any of them by Vitali-reaction. It was established that this violet coloration is due to the mesomerization of carb-anion in the alkaline solution.