The Effect of Maternal Dietary Restriction on the Growth and Development of Offsprings

식이제한(食餌制限)이 후손(後孫)의 성장발달(成長發達)에 미치는 영향(影響)

  • Kim, Hyun-Sook (Department of Food and Nutrition Ewha Women's University) ;
  • Kim, Sook-He (Department of Food and Nutrition Ewha Women's University)
  • 김현숙 (이화여자대학교 가정대학 식품영양학과) ;
  • 김숙희 (이화여자대학교 가정대학 식품영양학과)
  • Published : 1969.03.30

Abstract

Thirty female and six male rats aged fourty days were divided into two groups in order to feed them by pairfeeding for 50% dietary restriction in the pair group two weeks interval. Each group contains 15 female and three male rats matched each rat between two groups in consideration of body weight. Two female groups, one fed by 50% restricted diet and other Ad Libitum were divided into four groups each by the duration of dietary restriction during pregnancy: First ten days dietary restriction at 50% level, Last ten days dietary restriction at 50% level, Dietary restriction at 50% level for full period, And dietary unrestriction for full period Urinary total nitrogen and creatinine were determined. The birth weights of offsprings were decreased partial and full period dietary restriction of pregnant rats. There was no significant difference in the litter size of progeny due to the maternal diets. The growth was stunted in offsprings from the mothers fed restricted diet at 50% level for full period of pregnancy. No effect in the body weight gain of offsprings was observed in account of partial period of maternal dietary restriction. The urinary nitrogen of offsprings from eight different groups did not show any statistically significant difference.

임신 전(前) Restricted diet을 먹은 것과 Unrestricted diet을 먹은 group간에 2세의 체중증가에 미치는 영향에는 차이가 없었으며 임신 전(前) 체중변화에 있어서 Restricted diet에 숫컷이 더 예민하였다. 암컷에서는 Recovery diet을 주는 기간에는 Unrestricted group을 거의 쫓아 갔으나 숫컷에서는 그차이가 심하였다. 새끼들의 체중에 있어서 임신동안의 초기와 후기의 식이제한 group은 관계없이 임신전(全)기간 식이제한 group과 Unrestricted group간에 체중의 차이를 나타내었다. 어미의 Nitrogen 배설량에서 보면 섭취량에 대한 배설량의 백분율은 사료섭취량의 증감(增減)에 관계없이 일정하며 배설량은 사료섭취량이 많으면 많이 나가고 적으면 그것에 비례해서 적게 배설되었다. 새끼의 Nitrogen 배설량은 8 group사이에 큰 차이를 보여주지 않고 있다. Birth weight는 임신전(前) Restricted diet이나 Unrestricted diet 영향을 받지 않았으며 임신동안의 Unrestricted group의 새끼가 임신동안 전(全)기간 식이제한을 하였거나 부분적으로 식이제한을 한 group의 새끼보다 Birth weight가 컸다. litter size는 사료섭취량에 영향을 받지 않았다.

Keywords