Reaction of Nitrous Acid on 5-Aminopyrimidine Derivatives [Ⅱ] Isobarbituric Acid, A New Method of Synthesis

5-Aminopyrimidine에 대한 아질산의 작용 [Ⅱ] Isobarbituric acid의 새 합성법

  • Chang Sae Hee (Department of Chemistry, College of Liberal Arts and Sciences, Seoul National University) ;
  • Kim In Kyu (Department of Chemistry, College of Liberal Arts and Sciences, Seoul National University) ;
  • Hahn Bo-Sup (Department of Chemistry, College of Liberal Arts and Sciences, Seoul National University)
  • 장세희 (서울대학교 문리과대학 화학과) ;
  • 김인규 (서울대학교 문리과대학 화학과) ;
  • 한보섭 (서울대학교 문리과대학 화학과)
  • Published : 19650600

Abstract

A new method of synthesis of isobarbituric acid is described. With this method, isobarbituric acid can be synthesized both directly and conveniently. Yields of isobarbituric acid are up to 75 per cent.

5-Aminouracil을 디아조화한 다음 가수분해시켜 간편하게 isobarbituric acid를 합성하는 새로운 방법을 마련하였다. 이 방법에 따르면 전혀 부반응이 일어나지 않고 대체로 75%이상의 좋은 수율로 isobarbituric acid의 합성이 가능하다.

Keywords

References

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