Influence of Ascorbic Acid on Velocity Constant of Carboxyhemoglobin Dissociation

Ascorbic Acid가 Carboxyhemoglobin의 해리속도항수에 미치는 영향

Author has determined the dissociation velocity constant of carboxyhemoglobin in cattle blood solution by addition of ascorbic acid at $36-38{\deg}.$ It was found that these kinetic data are concordant with Roughton's equation d[COHb]/dt = $m^{'}[CO][O_{2}Hb]/[O_{2}$ - m[COHb] and that the dissociation velocity constant of carboxyhemoglobin was accelerated by the presence of ascorbic acid from 0.119 to 0.135.