Studies on the Syntheses of Orotic Acid Dervatives I. Synthesis of Orotyl-$_{DL}$-alanine and Orotyl-$_{L}$-tyrosine.

Orotic Acid 유도체의 합성에 관한 연구(I) Orotyl-$_{DL}$-alanine 및 Orotyl-$_{L}$-tyrosine의 합성

Two new orotic acid derivatives orotyl-DL-alanine and orotyl-L-tyrosine were synthesized. They were obtained as high melting crystalline masses by condensing DL-alanine and L-tyrosine each with orotyl chloride in aqueous sodium hydroxide solution, followed by acidifying the reaction mixture.