원지 Saponin 및 원지유가 가토의 혈청 Cholesterol 함량에 미치는 영향

Effects of Total Saponin and Oil Fraction of Polygala tenuifolia on Serum Cholesterol Level in Rabbits

Total saponin and oil fraction of Polygala tenuifolia were tested for their anticholesterolemic properties by a "Three day fasting method" on rabbits. It has been reported that saponin have the anticholesterolemic activity, however this activity is not general property of all kinds of saponin. As shown in Table, Polygala saponin has not significant anticholesterolemic activity on rabbits. On administering oil fraction of Radix Polygala, serum cholesterol level in rabbits increased to 224.7% while the control group 43.2%.oup 43.2%.