Korean Journal of Veterinary Research (대한수의학회지)

The Korean Society of Veterinary Science (대한수의학회)
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PATHOLOGIC STUDIES ON SODIUM MONOFLUOROACETATE (COMPOUND 1080) POISONING IN RABBITS

Sodium monofluoroacetate (Compound 1080) 중독(中毒)에 관(關)한 가토(家兎)의 병리해부학적(病理解剖學的) 연구(硏究)

  • Kim, Hwa Sik (Laboratory of Veterinary Pathology, Kyungbook National University)
  • 김화식 (경북대학교 수의병리학교실)
  • Published : 1961.06.01
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Abstract

Many losses in domestic animals have bern reported in this country, since sodium monofluoroacetate (Compound 1080) was used as a rodenticide. Lesions described inclubed multiple petechiae in epi- and endocardium, lung and intestinal mucosa, or superficial necrosis of the gastric mucosa. In this studies as to the poisoning 7 rabbits were administered 0.6mg (Group I), 0.4mg (Group II), and 0.3mg (Group III) of sodium monofluoroacetate per kilogram of body weight. and the results obtained were as follows: In addition to the changes mentioned above fatty degeneration in central parts of hepatic lobule or nut meg liver, haemorrhagic feci in cerebral cortex and leptomeninges and fatty degeneration in kidney and cardiac muscles were found.

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