Acknowledgement
본 연구는 국내 육성 감자 품종 부산물의 생리 활성 구명 및 식품소재 개발사업(사업번호: PJ0160522022)의 지원에 의해 이루어진 결과로 이에 감사드립니다.
Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2023.04a
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- Pages.39-39
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- 2023
Vasodilatation Effect of Complex Saponin Separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla Mixture Extract
- Jung Hwan Nam (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Jong Nam Lee (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Su hyoung Park (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Su Jeong Kim (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration) ;
- Do Yeon Kim (Highland Agriculture Research Institute, National Institute of Crop Science, Rural Development Administration)
- Published : 2023.04.27
Abstract
The purpose of this study is to investigate vasodilatation effect of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract on rabbit carotid artery. In this study, to determine vasodilatation effect of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract on rabbit carotid artery, arterial rings with intact or damaged endothelium were used for experiment using organ bath, and were contracted by endothelin. complex saponin, major active constituents of Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract, showed a moderate vasodilatation effect on the basilar arteries of rabbits. Therefore, treatment with complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract may selectively accelerate cerebral blood flow through dilatation of the basilar artery. Theseis result suggest a potential role of complex saponin separated from Scrophulariae radix, Asparagus cochinchinensis and Liriope platyphylla mixture extract as source of vasodilatation agent.
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