Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2019.04a
- /
- Pages.115-115
- /
- 2019
Anti-inflammatory effect of Arctium minus on LPS-stimulated RAW 264.7 cells
- Yang, Hye-Ji (Department of Biomedical Science, Jungwon University) ;
- Jang, Min-Hye (Department of Biomedical Science, Jungwon University) ;
- Kang, Yoon Joong (Department of Biomedical Science, Jungwon University)
- Published : 2019.04.25
Abstract
Arctium minus (AM), commonly known as lesser burdock, is a dried fruit (seed) of Aructium lappa L. that belong to Asteraceae. It has been used traditionally as herbal medicine because of its anti-inflammatory effects, and it has been applied to treat various diseases like allergies, skin aging, hyperlipidemia and urinary stone. In this study, we investigated the inhibitory effects of AM on the production of pro-inflammatory cytokines in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells. Pre-treatment of the RAW 264.7 cells with AM considerably inhibited and reduced production of Nitric Oxide (NO) and pro-inflammatory cytokines, such as interleukin (IL)-6 and tumor necrosis factor-