과제정보
연구 과제 주관 기관 : Korea Forestry Promotion Institute
한국자원식물학회:학술대회논문집 (Proceedings of the Plant Resources Society of Korea Conference)
- 한국자원식물학회 2018년도 추계학술대회
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- Pages.92-92
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- 2018
Chemical Constituents of Silene seulensis Nakai from Demilitarized Zone(DMZ)
- Jung, Yeon Woo (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Seo, Chan Gon (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Lee, Ji Eun (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Hong, Seong Su (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Kwon, Jin Gwan (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Shin, Hyun Tak (DMZ Botanic Garden, Korea National Arboretum) ;
- Jung, Su Young (DMZ Botanic Garden, Korea National Arboretum) ;
- Choi, Jeong Jun (College of Korean Medicine, DaeJeon University) ;
- Choi, Chun Whan (Bio-Center, Gyeonggido Business and Science Accelerator) ;
- Kim, Jin Kyu (Bio-Center, Gyeonggido Business and Science Accelerator)
- 발행 : 2018.10.08
초록
Silene seulensis Nakai was used as traditional medicines in Korea, we collected plant from demilitarized zone (DMZ). S. seulensis was extracted with 30, 50, and 70% ethanol and partitioned successively with n-hexane, EtOAc, dichloromethane and BuOH. These extracts (30, 50 and 70% ethanol) were evaluated the cytotoxicity on B16F10 and Hacat cell lines. The LC-MS/MS data of each fractions (n-hexane, EtOAc, dichloromethane, and BuOH) were compared with MS library, combined with ultraviolet/visual (UV/Vis) and MS data for faster determine structure by database search results. This led to the identification of four compounds (1-4) from S. seulensis. These compounds was isolated first time from S. seulensis. Their chemical structures are elucidated by combinations of NMR and mass spectrometry techniques.