한국자원식물학회:학술대회논문집 (Proceedings of the Plant Resources Society of Korea Conference)
- 한국자원식물학회 2018년도 춘계학술발표회
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- Pages.106-106
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- 2018
Cyanidin 3 - rutinoside chloride (CRC) Regulates Pro-inflammatory Mediators in PMACI-stimulated HMC-1 Cells
- Jeon, Yong-deok (Department of Oriental Medicine Resource, Chonbuk National University) ;
- AYE, AYE (Department of Oriental Medicine Resource, Chonbuk National University) ;
- Song, Young-Jae (Department of Oriental Medicine Resource, Chonbuk National University) ;
- Soh, Ju-Ryoun (Department of Oriental Medicine Resource, Chonbuk National University) ;
- Jin, Jong-Sik (Department of Oriental Medicine Resource, Chonbuk National University)
- 발행 : 2018.04.27
초록
Cyanidin 3 - rutinoside chloride (CRC) is major anthocyanin, found in Schisandra chinensis, is known to have antioxidant, anticancer, anti-inflammatory, tonic, and anti-aging effects in Korea, China and Japan. In the present study, the human mast cell line (HMC-1) was used to investigate the effects on the production of pro-inflammatory mediators. In this study, CRC showed no cytotoxicity in HMC-1. CRC significantly inhibited the secretion of inflammatory cytokines such as tumor necrosis factor