Proceedings of the Plant Resources Society of Korea Conference (한국자원식물학회:학술대회논문집)
- 2018.04a
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- Pages.94-94
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- 2018
Fruit Mediated Synthesis of Gold and Silver Nanoparticles Using Lycium chinense and Their Antimicrobial Activity
- Chokkalingam, Mohan (Graduate School of Biotechnology and Ginseng Bank, College of life Science, Kyung Hee University) ;
- Huo, Yue (Department of Oriental Medicinal Biotechnology, College of Life Science, Kyung Hee University) ;
- Kang, Jong-Pyo (Department of Oriental Medicinal Biotechnology, College of Life Science, Kyung Hee University) ;
- Mathiyalagan, Ramya (Graduate School of Biotechnology and Ginseng Bank, College of life Science, Kyung Hee University) ;
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Kim, Yoen-Ju
(Department of Oriental Medicinal Biotechnology, College of Life Science, Kyung Hee University) ;
- Yang, Deok-Chun (Graduate School of Biotechnology and Ginseng Bank, College of life Science, Kyung Hee University)
- Published : 2018.04.27
Abstract
The gold (LC-AuNPs) and silver (LC-AgNPs) nanoparticles were rapidly synthesized by fruit extract of Lycium chinense within 1.15 and 25 min respectively in an eco-friendly way. The synthesized nanoparticles confirmed by relevant surface plasmon resonance peaks for gold and silver nanoparticles at 536 and 480 nm, respectively. FE-TEM results revealed that LC-AuNPs were 20-50 nm and LC-AgNPs were 50-100 nm. The maximum distribution of gold, silver elements and the crystallographic nature of synthesized were confirmed using EDX, elemental mapping and XRD. LC-AgNPs showed inhibitory activity against pathogenic microorganisms such as E. coli and S. aureus, whereas LC-AuNPs did not show inhibitory activity. The LC-AgNps nanoparticles exhibited significant cytotoxicity to human breast cancer MCF7 cell line and less cytotoxicity to non-diseased RAW264.7 (murine macrophage) cells whereas LC-AuNps showed minimal toxicity to both cell lines. In-depth research on this rapid, facile and greenery nanoparticles may play a potential role in biomedical applications.
Keywords
- L. chinense;
- Gold nanoparticles;
- Silver nanoparticles;
- Antibacterial activity;
- Cytotoxicity;
- Breast cancer