Computational Study on the Binding of Aux/IAA17 and ARF5 Involved in Auxin's Transcriptional Regulation using Molecular Docking

  • Kwon, Sohee (Department of Chemistry, Seoul National University) ;
  • Lee, Gyu Rie (Department of Chemistry, Seoul National University) ;
  • Seok, Chaok (Department of Chemistry, Seoul National University)
  • Published : 2017.03.24

Abstract

Auxin response factor (ARF) and Aux/IAA transcriptional repressor family proteins play a major role in auxin's signalling process. Using the GALAXY protein modelling programs, monomer, dimer and oligomer structures of Aux/IAA17 and ARF5 protein were predicted based on the known experimental structures. By analysing the proposed complex structures, key interacting residues on binding site could be determined, and further suggestions for experimental studies were made.

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