Detection Property of Red Blood Cell-Magnetic Beads Using Micro Coil-Channel and GMR-SV Device

  • Park, Ji-Soo (Dept. of Oriental Biomedical Engineering Sangji University) ;
  • Kim, Nu-Ri (Dept. of Oriental Biomedical Engineering Sangji University) ;
  • Jung, Hyun-Jun (Dept. of Oriental Biomedical Engineering Sangji University) ;
  • Khajidmaa, Purevdorj (Dept. of Oriental Biomedical Engineering Sangji University) ;
  • Bolormaa, Munkhbat (Dept. of Oriental Biomedical Engineering Sangji University) ;
  • Lee, Sang-Suk (Dept. of Oriental Biomedical Engineering Sangji University)
  • Published : 2015.05.28

Abstract

The micro device, coil, and channel for the biosensor integrated with the GMR-SV device based on the antiferromagnetic IrMn layer was fabricated by the light lithography process. When RBCs coupled with several magnetic beads with a diameter of $1{\mu}m$ passed on the micro channel, the movement of RBC + ${\mu}Beads$ is controlled by the electrical AC input signal. The RBC + ${\mu}Beads$ having a micro-magnetic field captured above the GMR-SV device is changed as the output signals for detection status. From these results, the GMR-SV device having the width magnitude of a few micron size can be applied as the biosensor for the analysis of a new magnetic property as the membrane's deformation of RBC coupled to magnetic beads.

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