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Construction of an Effectiveness Network to Identify Dynamical Interaction of Genes

  • Mazaya, Maulida (School of Computer Engineering and Information Technology, University of Ulsan) ;
  • Kwon, Yung-Keun (Dept. of Computer Engineering, University of Ulsan)
  • Published : 2014.11.05

Abstract

Interactions between genes have long been recognized and studied by many researchers, and they formed a large-scale interaction networks. In systems biology, it has been a challenge to investigate the factors to determine network dynamics. Here, we create a new network called an effectiveness network by calculating thy dynamical effectiveness from a node to another node. We found that robust nodes tend to have smaller number of edges than non-robust nodes. This implies that hub nodes are likely to affect the network robustness.

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