한국약용작물학회:학술대회논문집
- 2010.10a
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- Pages.430-430
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- 2010
Rapid Identification of the ${\alpha}$ -Glucosidase Inhibitory Compounds from Geranium thunbergii Sieb. et Zucc. by HPLC-micro-fractionation and HPLC-UV-$MS^n$
- Choi, Se-Jin (Department of Food Science and Nutrition, Hallym University) ;
- Kim, Jin-Kyu (Institute of Natural Medicine, Hallym University) ;
- Lee, Yeon-Sil (Center for Efficacy Assessment and Development of Functional Foods and Drugs, Hallym University) ;
- Lim, Soon-Sung (Department of Food Science and Nutrition, Hallym University)
- 최세진 ;
- ;
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- Published : 2010.10.12
Abstract
In this study ethanol extracts of aerial part of Geranium thunbergii Sieb. et Zucc. was investigated for their ability to inhibit a-glucosidase, and thus was fractionated using two organic solvents, including dichloromethane, ethyl acetate. The ethyl acetate-soluble fraction, which manifested potent enzyme inhibitory properties, was then followed by tracking down the active compound by combining HPLC micro-fractionation to an enzyme assay in 96-well plate. The
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