대한기계학회:학술대회논문집 (Proceedings of the KSME Conference)

대한기계학회 (The Korean Society of Mechanical Engineers)
권호 표지

마이크로 유체 칩을 이용한 세포행태에 관한 연구

Cell behavior study using microfluidic chip

  • 박중열 (고려대학교 보건과학대학 생체의공학과)) ;
  • 이상훈 (고려대학교 보건과학대학 생체의공학과))
  • Park, Joong-Yull (Department of Biomedical Engineering, College of Health Science, Korea University) ;
  • Lee, Sang-Hoon (Department of Biomedical Engineering, College of Health Science, Korea University)
  • 발행 : 2008.11.05
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초록

In the conventional biology, the most of cell studies was carried out by culturing cells in the Petri dish and by investigating cellular behavior under the diverse bio-molecule (cell signalling materials, drugs or etc.) conditions. However, in vivo environments, diverse stimulations including chemical, mechanical and topological environments involved in the proliferation, differentiation and migration of cells and it is almost impossible to provide these conditions with traditional method. We have developed the methods to provide the well defined chemical and mechanical stimulations using microfluidic devices and applied these approaches to the study of environmental effect on cells. In this paper, we will introduce our microfluidic chips to provide microenvironment and its applications using several cells.

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