대한기계학회:학술대회논문집 (Proceedings of the KSME Conference)

대한기계학회 (The Korean Society of Mechanical Engineers)
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Characterization of HA/PCL composite scaffolds fabricated by layer manufacturing technology

  • Kim, Seung-Eon (Center for Future Technology, Korea Institute of Materials Science) ;
  • Hyun, Yong-Taek (Center for Future Technology, Korea Institute of Materials Science) ;
  • Yun, Hui-Suk (Center for Future Technology, Korea Institute of Materials Science) ;
  • Yoon, Taek-Rim (Center for Joint Deseases, Chonnam National University Hwasun Hospital) ;
  • Heo, Su-Jin (Department of Biomedical Engineering, Inje University) ;
  • Shin, Jung-Woog (Department of Biomedical Engineering, Inje University)
  • 발행 : 2008.11.05
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초록

Layer manufacturing technology has been recently spotlighted as a promising candidate to fabricate porous scaffolds for tissue engineering, because it can provide three dimensional interconnectivity and different pore structures and on-demand scaffold design. This study aims to fabricate HA/PCL composite scaffolds for bone tissue engineering by a layer manufacturing technology, paste extruding deposition, and to characterize in vitro and in vivo biocompatibilities of the scaffolds. This study discusses the mechnical properties, proliferation and differentiation of osteogenic cells, and tissue in-growth and bone regeneration behavior using animal models.

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