Fabrication of Biochip by Hydrophobic Interaction

무작위 조립법을 이용한 바이오칩의 제작

  • Choi, Yong-Sung (Department of Electrical Engineering, DongShin University) ;
  • Moon, Jong-Dae (Department of Electrical Engineering, DongShin University) ;
  • Lee, Kyung-Sup (Department of Electrical Engineering, DongShin University)
  • Published : 2006.06.22

Abstract

Microarray-based DNA chips provide an architecture for multi-analyte sensing. In this paper, we report a new approach for DNA chip microarray fabrication. Multifunctional DNA chip microarray was made by immobilizing many kinds of biomaterials on transducers (particles). DNA chip microarray was prepared by randomly distributing a mixture of the particles on a chip pattern containing thousands of m-scale sites. The particles occupied a different sites from site to site. The particles were arranged on the chip pattern by the random fluidic self-assembly (RFSA) method, using a hydrophobic interaction for assembly.

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