한국생물공학회:학술대회논문집

The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
권호 표지

Study on the Antimicrobial Activities of Natural Products

  • Choi, Mi-Jung (Dept. of Applied Chemical Engineering, Korea Univ. of Tech. & Edu.) ;
  • Lee, Yun-Hee (Dept. of Applied Chemical Engineering, Korea Univ. of Tech. & Edu.) ;
  • Shin, Chun-Hwa (Dept. of Applied Chemical Engineering, Korea Univ. of Tech. & Edu.) ;
  • Koo, Ja-Kyung (Dept. of Applied Chemical Engineering, Korea Univ. of Tech. & Edu.) ;
  • Jang, Dong-Il (Cotde Co. Inc.) ;
  • Cho, Nam-Jun (Dept. of Applied Chemical Engineering, Korea Univ. of Tech. & Edu.)
  • Published : 2005.10.27
Download PDF
⟨ Previous Next ⟩

Abstract

The antimicrobial activities of extracts from some of natural products and bacteriocins produced from lactic acid bacteria such as L. mesenteroides, L. citreum and P. pentosaceus have been investigated with using disc diffusion assay, challenge method and minimum inhibitory concentration method. The bacteriocin substances produced from L. mesenteroides, L. citreum and P, pentosaceus have shown strong antimicrobial activities against E. coli, S. aureus, P. aerugionosa, and B. subtillis while the extracts from phenonip and sandal wood have shown strong antimicrobial activities only against C. albicans. The bacteriocins produced from L. mesenteroides, L. citreum and P. pentosaceus could be a promising preservatives for cosmetics, pharmaceutical products and foods in future.

항균력이 있는 것으로 예측되는 몇몇 천연물로부터의 추출물과 유산균인 L. mesenteroides, L. citreum, P. pentosaceus의 대사산물인 박테리오신의 항균특성을 알아보기 위하여 최소억제농도 (MIC) 측정법, disc diffusion assay와 challenge법으로 항균력을 조사하였다. L. mesenteroides, L. citreum, P. pentosaceus 유산균에 의해 생산된 박테리오신은 P. aeruginosa, S. aureus, E. coli, B. subtillis 균에 대하여 뛰어난 항균특성을 보인 반면 C. albicans에 대해서는 상대적으로 약한 항균력을 보였다. 반면에 phenonip과 sandal wood 추출물은 C. albicans에 대해서는 강한 항균력을 나타냈으나 다른 대표균들에 대해서는 매우약하거나 거의 항균력을 나타내지 않았다.

Keywords