한국생물공학회:학술대회논문집
- 2005.04a
- /
- Pages.566-569
- /
- 2005
Applications of Extracellular Polysaccharide p-m10356
- Park, Hee-Jung (Department of Material & Biochemical Engineering, Chonnam National University) ;
- Kim, Hyong-Ju (Interdisciplinary Program of Biomedical Engineering, Chonnam National University) ;
- Lee, Chang-Moon (Interdisciplinary Program of Biomedical Engineering, Chonnam National University) ;
- Kim, Jin (Interdisciplinary Program of Perfume and Cosmetics, Chonnam National University) ;
- Lee, Hong-Kum (Korea Ocean Rearch & Developement Institute) ;
- Yim, Joung-Han (Korea Ocean Rearch & Developement Institute) ;
-
Lee, Ki-Young
(Faculty of Applied Chemical Engineering, Chonnam National University)
- Published : 2005.04.15
Abstract
The extracellular polysaccharide...(EPS) has been used in a wide variety of industrial applications because of gel formation, emulsion stability, control of the surface tension, water absorption and film formation etc. In this study, inhibitory activity on tyrosinase and inhibitory activity on angiotensin converting enzyme...(ACE) are determined. UV adsorption wavelength, beads formation of EPS were investigated. In the result, in 1%(w/v) EPS concentration, EPS had inhibitory activity of 71.8% on tyrosinase and inhibitory activity of 61.5% on angiotensin converting enzyme in 1.5% EPS concentration. Adsorption wavelength of EPS was UV-B,C . Beads based on EPS were prepared by w/o emulsion method and the shape of EPS beads observed by SEM was spherical and uniform.
tyrosinase 저해 활성 실험 결과 1.2%(w/v) 이상의 농도에서 70% 이상의 저해를 나타내 색소침착에 대한 기능성 화장품 원료로 사용이 가능할 것으로 보이며, ACE 저해 활성 실험에서 1.5% 농도에서 60% 가량의 저해활성을 보여 혈관 변형 치료 및 예방에 효과가 있을 것으로 기대된다. UV 흡수능에서는 UV-B, UV-C의 영역에서 흡수 경향을 나타내며 자외선 차단제의 원료로 사용이 가능할 것으로 기대되며, 또한 bead 형성능을 가지고 있어 약물전달체로서 이용 가능성이 기대된다.
Keywords