A Unified Object Database for Biochemical Pathways

  • Jung, T.S. (Dept. of Information Industrial Engineering, Chungbuk National University) ;
  • Oh, J.S. (Dept. of Management Information System, Chungbuk National University) ;
  • Jang, H.K. (Dept. of Management Information System, Chungbuk National University) ;
  • Ahn, M.S. (Dept. of Management Information System, Chungbuk National University) ;
  • Roh, D.H. (Schools of Life Science, Chungbuk National University) ;
  • Cho, W.S. (Dept. of Management Information System, Chungbuk National University)
  • Published : 2005.09.22

Abstract

One of the most important issues in post-genome era is identifying functions of genes and understanding the interaction among them. Such interactions from complex biochemical pathways, which are very useful to understand the organism system. We present an integrated biochemical pathway database system with a set of software tools for reconstruction, visualization, and simulation of the pathways from the database. The novel features of the presented system include: (a) automatic integration of the heterogeneous biochemical pathway databases, (b) gene ontology for high quality of database in the integration and query (c) various biochemical simulations on the pathway database, (d) dynamic pathway reconstruction for the gene list or sequence data, (e) graphical tools which enable users to view the reconstructed pathways in a dynamic form, (f) importing/exporting SBML documents, a data exchange standard for systems biology.

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