한국생물정보학회:학술대회논문집 (Proceedings of the Korean Society for Bioinformatics Conference)
- 한국생물정보시스템생물학회 2005년도 BIOINFO 2005
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- Pages.41-44
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- 2005
Discovery of Novel 4${\alpha}$ helix Cytokine by Hidden Markov Model Analysis
- Du, Chunjuan (School of Mathematical Sciences, South China Normal University, College of Life science and Bioengineering, Beijing University of Technology, Laboratory of Genomics and Proteomics, Beijing Institute of Radiation Medicine) ;
- Zeng, Yanjun (College of Life science and Bioengineering, Beijing University of Technology) ;
- Zhu, Yunping (Laboratory of Genomics and Proteomics, Beijing Institute of Radiation Medicine) ;
- He, Fuchu (Laboratory of Genomics and Proteomics, Beijing Institute of Radiation Medicine)
- 발행 : 2005.09.22
초록
Cytokines play a crucial role in the immune and inflammatory responses. But because of the high evolutionary rate of these proteins, the similarity between different members of their family is very low, which makes the identification of novel members of cytokines very difficult. According to this point, a new bioinformatic strategy to identify novel cytokine of the short-chain and long-chain 4
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