Proceedings of the KSME Conference (대한기계학회:학술대회논문집)
- 2004.04a
- /
- Pages.1682-1686
- /
- 2004
Measurements of RBC deformability and its effect on blood viscosity
적혈구 변형성의 측정과 혈액 점도와의 상관관계 연구
- Ku, Yun-Hee (Graduate, Kyungpook National University) ;
- Park, Myung-Su (Graduate, Kyungpook National University) ;
- Shin, Se-Hyun (School of Mechanical Engineering, Kyungpook National University)
- Published : 2004.04.28
Abstract
A slit-flow apparatus with laser diffraction method has been developed with significant advances in ektacytometry design, operation and data analysis. In the slit-flow ektacytometry (or laser-diffractometry), the deformation of red blood cells subjected to continuously decreasing shear stress in slit flow is measured. A laser beam traverses a diluted blood suspension flowing through a slit and is diffracted by RBCs in the volume. The diffraction patterns are captured by a CCD-video camera, linked to a frame grabber integrated with a computer, while the differential pressure variation is measured by a pressure transducer. Both measurements of laser-diffraction image and pressure with respect to time enable to determine deformation index and the shear stress. The range of shear stress of 0