Treatment to induce long-term non-progressor with constant drug dosage

일정한 약물 투여를 통한 HIV 환자의 long-term non-progressor 전환 치료

  • Kim, Jin-Young (Division of Electrical and Computer Engineering, Hanyang University) ;
  • Kim, Won-Hee (Division of Electrical and Computer Engineering, Hanyang University) ;
  • Ko, Ji-Hyun (Division of Electrical and Computer Engineering, Hanyang University) ;
  • Chung, Chung-Choo (Division of Electrical and Computer Engineering, Hanyang University)
  • 김진영 (한양대학교 전자전기컴퓨터 공학부) ;
  • 김원희 (한양대학교 전자전기컴퓨터 공학부) ;
  • 고지현 (한양대학교 전자전기컴퓨터 공학부) ;
  • 정정주 (한양대학교 전자전기컴퓨터 공학부)
  • Published : 2004.07.14

Abstract

This paper presents a therapy that uses a constant drug dosage for leading a HIV patient to a LTNP (Long-Tenn Non-Progressor). From analysis of CTLp (Cytotoxic T Lymphocyte precursor) concentration at equilibrium point and bifurcation of equilibrium points, we found the therapy with a drug whose efficacy is less than one brings higher CTLp concentration at the equilibrium point. From this fact, we propose a treatment with constant drug dosage. which can induce LTNP.

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