한국생물공학회:학술대회논문집
- 한국생물공학회 2003년도 생물공학의 동향(XIII)
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- Pages.655-659
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- 2003
Preparation of Eudragit coated solid lipid nanoparticles (SLN) for hydrophilic drug delivery
- Han, Sung-Chul (Department of Material & Biochemical Engineering Chonnam National University) ;
- Yoon, Hee-Sun (Department of Material & Biochemical Engineering Chonnam National University) ;
- Lee, Ki-Young (Faculty of Applied Chemical Engineering, Chonnam National University) ;
- Kim, Yeon-Zu (Department of Skin and Beauty, Kwangju Health College & Polymer Engineering, Chonnam National University) ;
- Kim, Dong-Woon (Department of Environmental Science, kwangyang Health college, Nanobiomed Inc.)
- 발행 : 2003.10.22
초록
수용성 약물의 캡슐화 효율을 높이기 위하여 eudragit이 코팅된 SLN을 제조하였고 TEM을 이용하여 그 형태가 양호하게 형성된 것을 확인하였다. DLS를 이용하여 형성된 입자의 분포와 크기를 확인하였으며 옥용산을 포함하는 E-SLN은
Solid lipid nanoparticle (SLN) system has been attracted increasing attention during last few years as a potential drug delivery carrier However, the SLN have disadvantage of low encapsulation efficiency for hydrophilic drug. In this study, for increase it's encapsulation efficiency, we prepared the
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