Changes in Cell Cycle-related Genes Expression of Chineses Hamster Ovary Cells cultured using Serum-free Media

  • Seo, Sung-Keum (Dept. of Microbial engineering, Konkuk University) ;
  • Park, Hong-Woo (Dept. of Chemical engineering, Hanyang University) ;
  • Choe, Tae-Boo (Dept. of Microbial engineering, Konkuk University)
  • Published : 2003.10.22

Abstract

The genome-wide program of gene expression during the cell division cycle response to serum free media in chinese hamster ovary(CHO) cells was characterized using cDNA microarrays. Many transcripts of genes showed variation during the cell cycle. Characterization is critical step toward understanding the basic cell cycle processes and serum-free media role in CHO cells

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