대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.228.2-229
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- 2003
Study on Polymorphism of Cefotaxime Sodium, Cephradine, and Ceftriaxone Sodium
- Park, Sun-Hee (College of Pharmacy, Dongduk Women's University) ;
- Sohn, Young-Taek (College of Pharmacy, Dongduk Women's University)
- 발행 : 2003.10.01
초록
Investigation of polymorphism has become a requirement in the pharmaceutical industry because the physical properties and bioavailabilities of crystalline drugs depend on their polymorphic form. Two polymorphic modifications and one pseudopolymorphic modification of cefotaxime sodium were prepared by recrystallization in organic solvents under variable conditions. Four polymorphic modifications of cephardine were prepared by recrystallization. Three polymorphic modifications and one pseudopolymorphic modification of ceftriaxone sodium were prepared by recrystallization. (omitted)
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