Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
권호 표지

Poly(l-lactide) membranes with biomimetic nanolayer for bone induction for tissue regeneration

  • Chung , Ji-Eun (Department of Pharmacy, College of Pharmacy, Ewha womans University) ;
  • Lee, Jue-Yeon (Department of Periodontology, College of Dentistry, Seoul National University) ;
  • Kim, Kyung-Hwa (Department of Periodontology, College of Dentistry, Seoul National University) ;
  • Baek, Hyun-Jin (Department of Periodontology, College of Dentistry, Seoul National University) ;
  • Ku , Young (Department of Periodontology, College of Dentistry, Seoul National University) ;
  • Chung, Chong-Pyung (Department of Periodontology, College of Dentistry, Seoul National University) ;
  • Lee, Seung-Jin (Department of Periodontology, College of Dentistry, Seoul National University)
  • Published : 2003.10.01
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Abstract

.The healing of a bone defect is complex, and involves a wide range of cellular, molecular, physiological, and biological processes. The main effect of bone substitute is to promote wound healing by induce cell proliferation. Bone defect sites usually are localized below the original bone surface; therefore, space production and maintenance between the membrane and the original bone surface is essential. As a result, membranes must have proper mechanical strength to prevent the collapse of the soft tissue and maintain wound space that permits membranes of poly (L-lactide) (PLLA) were fabricated to provide and maintain sufficient space for bone growth. (omitted)

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