Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.216.1-216.1
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- 2003
Cyclooxygenase Inhibitory Activity of Ginsenosides from Panax ginseng
- Yoo, Hye-Hyun (College of Pharmacy, Seoul National University) ;
- Kang, Ki-Sung (College of Pharmacy, Seoul National University) ;
- Lee, Yang-Beom (College of Pharmacy, Seoul National University) ;
- Kim, Bak-Kwang (College of Pharmacy, Seoul National University) ;
- Park, Man-Ki (College of Pharmacy, Seoul National University) ;
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Park, Jeong-Hill
(College of Pharmacy, Seoul National University)
- Published : 2003.10.01
Abstract
P. ginseng C.A. Meyer is one of the most widely used herbal medicine in Asia. It has been used for the treatment of many disorders. Its major constituent is known to be ginsenosides, and there are many documents about bioactivities of ginsenosides such as anti-oxidant, anti-tumorigenic, anti-fatigue, and anti-inflammatory activities. Some of these activities are supposed to have some correlation with inhibitory action of cyclooxygenase (COX). Ginsenosides from P. ginseng and sapogenins were evaluated for their inhibitory effects against both cyclooxygenase-1 and -2 (COX-1 and -2). Inhibitory activity was evaluated by measuring prostaglandin E
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