Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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Simultaneous enantioseparation of $\beta$-blockers by chiral capillary electrophoresis in reversed polarity mode

  • Kim, Jiyung (School of Life Science and Engineering, Yonsei University) ;
  • Kim, Hang-Han (College of pharmacy, Sungkyunkwan University) ;
  • Kim, Kyoung-Rae (College of pharmacy, Sungkyunkwan University)
  • Published : 2003.10.01
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Abstract

The chiral separation of multiple ${\beta}$-blockers is described for their accurate chiral discrimination by chiral capillary electrophoresis (CE). The cyc1odextrin-modified CE system was operated in the reversed polarity mode. In this mode, fairly good enantiomeric resolutions were achieved. Relative migration times to internal standard under optimum conditions were characteristic of each enantiomer with good precision. Therefore, in this study, the usefulness for the chiral separation and accurate identification will be discussed.

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