대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.201.3-201.3
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- 2003
Cytoprotective Effect on Oxidative Stress and Inhibitory Effect on Cellular Aging of Terminalia chebula and Uncaria sinensis
- Na, Min-Kyun (Jakwang Research Institute, Hansaeng Cosmetics Co., Ltd) ;
- Hong, Nam-Doo (Department of Biotechnology, Hiroshima Prefectural University School of BioScience) ;
- Kamiryo Yuko (R&D Center, I.T.O. Co., Ltd) ;
- Senoo, Yu-Ichiro (R&D Center, I.T.O. Co., Ltd) ;
- Yokoo Seiichi (R&D Center, I.T.O. Co., Ltd) ;
- Ito Shinobu (R&D Center, I.T.O. Co., Ltd) ;
- Miwa Nobuhiko (R&D Center, I.T.O. Co., Ltd.)
- 발행 : 2003.10.01
초록
The ethanol extract from the fruit of Terminalia chebula (Combretaceae) and the hook of Uncaria sinensis (Rubiaceae) exhibited significant inhibitory activity on oxidative stress and the age-dependent shortening of the telomeric DNA length. In the peroxidation model using t-BuOOH, human epidermal keratinocytes-neonatal foreskin (HEK-N/F) cells were treated with the T. chebula and U. sinensis extracts. The results showed a notable enhancing effect on the cell viability of 60.5
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