Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.179.1-179.1
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- 2003
Preparation of Enantiomerically Pure Chiral builing block ((E)-4-(tributylstannanyl) but-3-en-2-ol) via lipase-mediated resolution
- Lee, Tae-Ho (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Ko, Hyo-Jin (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Lee, Hye-Seung (Natural Products Research Institute, College of Pharmacy, Seoul National University) ;
- Kim, Sang-Hee (Natural Products Research Institute, College of Pharmacy, Seoul National University)
- Published : 2003.10.01
Abstract
Chiral building blocks have the importance in the pharmaceutical and agrochemical industries as well as in the development of rapid and efficient syntheses of bioactive compounds and natural product. Vinylstannane contains two synthetically useful functional groups (vinylstannane and allylic alcohol). The vinylstannane functional group can be used in C-C bond formation under a variety of conditions and the allylic alcohol functional can be used in hydroxyl-directed epoxidations, cyclopropanations, and sigmatropic rearrangements. (omitted)
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