대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.174.3-175
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- 2003
Detection, Identification and Characterization of In vitro GSH Metabolites Formed by 1-and 2-Bromopropane
- Moon, Yoon-Soo (College of Pharmacy, Yeungnam University) ;
- Kim, Eun-Kyung (School of Medicine, Catholic University of Daegu) ;
- Basnet, Arjun (School of Medicine, Catholic University of Daegu) ;
- Zhao, Long-Xuan (School of Medicine, Catholic University of Daegu) ;
- Kim, Dae-Ok (School of Medicine, Catholic University of Daegu) ;
- Kim, Nam-Hee (School of Medicine, Catholic University of Daegu) ;
- Chae, Whi-Gun (School of Medicine, Catholic University of Daegu) ;
- Jeong, Tae-Cheon (School of Medicine, Catholic University of Daegu) ;
- Lee, Eung-Seok
- 발행 : 2003.10.01
초록
1-and 2-Bromopropane were reported as the causative agents for reproductive toxicity and immunotoxicity. The glutathione (GSH) metabolites resulting from in vitro treatment of 1- and 2-bromopropane were detected, identified and characterized. For the facile identification, expected GSH metabolites rormed by 1- and 2-bromopropane were chemically synthesized as reference materials (positive controls) and characterized by
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