Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.174.2-174.2
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- 2003
AHL inhibition of Beckerelide and Fimbrolide
- Kim, Yeon-Hee (Department of Chemical Engineering and Institute for Environmental Technology and Industry, Pusan National University) ;
- Lee, Jae-Gun (Department of Biotechnology, Dongseo University) ;
- Park, Sung-Hoon (Department of Biotechnology, Dongseo University) ;
- Kim, Jung-Sun (Department of Biotechnology, Dongseo University)
- Published : 2003.10.01
Abstract
Quorum sensing, a gene expression in response to population density, is regulated by chemical signals, most of which are acylated homoserine lactones (AHLs). The AHL derivatives have been reported to regulate bioluminescence, virulence factors and / or swarming motility in bacteria. It is hypothesized that higher organisms may have evolved specific means to interfere with bacterial communication as exemplified in the AHL-antagonistic activity of halogenated furanones isolated from the Australian macroalga Delisea pulchra. (omitted)
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