대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.151.1-151.1
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- 2003
Polyunsaturated fatty acids regulate APP metabolism.
- Yeon, Seung-Woo (ILDONG Research Laboratories, ILDONG Pharmaceutical Co. Ltd.) ;
- Kim, Tae-Yong (ILDONG Research Laboratories, ILDONG Pharmaceutical Co. Ltd.)
- 발행 : 2003.10.01
초록
Polyunsaturated fatty acids (PUFAs) play many important physiological roles on cellular process through the regulations of intracellular signaling. Recent clinical studies suggest that PUFAs such as n-3 fatty acids (docosahexaenoic acid, 22:6 and a-lnolenic acid, 18:3) may reduce the risk of incident Alzheimer's disease (AD). And also the reports regarding the decrease of n-3 fatty acids in AD brain support the correlation between PUFAs and AD. AD is a neurodegenerative disorder with pathological hallmarks of amyloid plaques and neurofibrillary tangles. (omitted)
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