대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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- Pages.137.1-137.1
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- 2003
Immunostimulatory Effect of Ginkgolides Enhances Resistance of Neutropenic Mice against Hematogenously Disseminated Candidiasis
- Lee, Jue-Hee (College of Pharmacy, Dongduk Women's University) ;
- Han, Yong-Moon (College of Pharmacy, Dongduk Women's University)
- 발행 : 2003.10.01
초록
We investigated immunoactivity of ginkgolides (GLS), the primary active constituent of Ginkgo biloba leaves, against disseminated candidiasis due to Candida albicans. This fungus is a polymorphic opportunistic pathogen. BALB/c mice were induced neutropenia by intraperitoneal (i.p.) injection of cyclophosphamide (CP) 24 hours before an i.p administration of GLS (2 mg/mouse) to the mice. Control mice received diluent (Dulbecco's phosphate saline solution; DPBS) instead of GLS. (omitted)
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