Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.90.3-91
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- 2003
Effects of E-4031 on hERG channel currents expressed in CHO cells in an accordance with temperature
- Kim, Eun-Joo (Korea Institute of Toxicology, KRICT) ;
- Kim, Ki-Suk (Korea Institute of Toxicology, KRIC) ;
- Shin, Won-Ho (Korea Institute of Toxicology, KRIC) ;
- Seo, Joung-Wook (Korea Institute of Toxicology, KRIC) ;
- Choi, Gyu-Kap (Korea Institute of Toxicology, KRIC) ;
- Park, Eun-Kyung (Korea Institute of Toxicology, KRIC) ;
- Hwang, Ji-Yoon (Korea Institute of Toxicology, KRIC) ;
- Han, Sang-Seop (Korea Institute of Toxicology, KRICT)
- Published : 2003.10.01
Abstract
The most commonly proposed mechanism for QT interval prolongation(LQT) by pharmaceuticals is inhibition of the rapid delayed rectifier potassium channel (I
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