Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.10b
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- Pages.65.3-66
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- 2003
Total Synthesis of Bacillariolide III
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Suh, Young-Ger
(College of Pharmacy, Seoul National University) ;
- Seo, Seung-Yong (College of Pharmacy, Chungbuk National University) ;
- Paek, Seung-Mann (College of Pharmacy, Chungbuk National University) ;
- Jung, Jae-Kyung (College of Pharmacy, Chungbuk National University) ;
- Han, Young-Taek (College of Pharmacy, Chungbuk National University) ;
- Kim, Seok-Ho (College of Pharmacy, Chungbuk National University)
- Published : 2003.10.01
Abstract
Bacillariolide III was isolated from the culture medium of the marine diatom, Pseudonitzschia multi series, a causative organism of amnesic shellfish poisoning by Shimizu et al. This extracellular metabolite features bicyclic system of hydroxycyclopentane and (Z)-pentenoic acid-bearing lactone ring. Bacillariolide I is known to possess significant inhibitory activity against phospholipase A
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