Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.311.2-312
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- 2003
BIOEQUIVALENCE EVALUATION OF FLUCONAZOLE 50 MG THREE CAPSULES IN HEALTHY MALE KOREAN VOLUNTEERS
- Kang, Hyun-Ah (College of Pharmacy and Institude of BE and Bridging Study, CNU) ;
- Baek, Seung-Hee (College of Pharmacy and Institude of BE and Bridging Study, CN) ;
- Kim, Eun-Hee (College of Pharmacy and Institude of BE and Bridging Study, CN) ;
- Lee, Yong-Bok (College of Pharmacy and Institude of BE and Bridging Study, CNU)
- Published : 2003.04.01
Abstract
The purposes of this study were to evaluate bioequivalence (BE) using In-transformed pharmacokinetic parameters obtained from two fluconazole products and to develop the analytical methods for the quantitative determination of fluconazole in human serum. In addition, the in vitro dissolution profiles of the two fluconazole products at dissolution media: 0.1 M hydrochloride (KP Ⅶ Apparatus II method) were assessed. (omitted)
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