Simultaneous determination of talniflumate and its metabolite in human plasma by high-performance liquid chromatography

  • Published : 2003.04.01

Abstract

Talniflumate is a potent analgesic and anti-inflammatory drug widely prescribed in rheumatoid diseases. The purpose of this work was to develop and validate a specific and robust method for the simultaneous determination of talniflumate and its metabolite, niflumic acid, in human plasma. Indomethacin was used as an internal standard (IS). (omitted)

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