Determination of meloxicam in human plasma by semi-micro high-performance liqiud chromatography.

  • Published : 2003.04.01

Abstract

This study describes a simple and sensitive semi-micro HPLC method with UV detection and direct deproteinization. The plasma protein was precipitated using perchloric acid (60%) and the supernatant was directly injected onto the semi-micro HPLC system. The separation was achieved on a C18 (25 mm ${\times}$ 2.0 mm I.D) analytical column with a mobile phase of sodium acetate buffer (pH 3.5, 50 mmol) - acetonitrile (60:40, V/V). (omitted)

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