Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.263.1-263.1
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- 2003
Saucerneol B with Hepatoprotective Effect of the Roots of Saururus chinensis
- Kim, Mi-Hee (Spela Co., Ltd.) ;
- Park, Eun-Jeon (College of Pharmacy, Wonkwang University) ;
- Jun, Jung-Yang (College of Pharmacy, Wonkwang University) ;
- Ko, Eun-Kyung (College of Pharmacy, Wonkwang University) ;
- Park, Sung-Eun (College of Pharmacy, Wonkwang University) ;
- Park, Sung-Uk (College of Pharmacy, Wonkwang University) ;
- Sohn, Dong-Hwan (College of Pharmacy, Wonkwang University) ;
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Kim, Youn-Chul
(College of Pharmacy, Wonkwang University)
- Published : 2003.04.01
Abstract
In order to find the new hepatoprotective agents from natural products, the isolation and identification of biological active components of the roots of Saururus chinensis has been carried out. A MeOH extract of this plant showed the significant hepatoprotective effect on tacrine-induced cytotoxicity in Hep G2 cells. Five lignans including sauchinone, manassantin A, manassantin B, saucerneol B, and di-O-methyltetrahydrofuriguaiacin B were isolated and identified by spectroscopic evaluation. (omitted)
Keywords