Proceedings of the PSK Conference (대한약학회:학술대회논문집)

The Pharmaceutical Society of Korea (대한약학회)
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A Chemical Component of the Marine Alga Ishige Okamurae

  • Kim, Eun-Sook (Dep. of Chemical Technology, Hanbat National University) ;
  • Choi, Byoung-Wook (Dep. of Chemical Technology, Hanbat National University) ;
  • Lee, Bong-Ho (Dep. of Chemical Technology, Hanbat National University)
  • Published : 2003.04.01
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Abstract

Marine Algae of order Chordariales are rich resources of bioactive metabolites. Methanolic extracts of the brown alga /shige Okamurae exhibited potent antioxidative and butyrylcholinesterase(BChE) inhibitory effects. Bio-guided purification [solvent partition, ODS flash, silica flash, gel-filtration on Sephadex LH 20, ODS HPLC] of them gave a compound 1. Its structure was elucidated by detailed analysis of spectroscopic data of 1 and comparison of literature data. A variety of bioassay for 1 is in progress.

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