대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.243.2-244
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- 2003
The Structure-Activity Relationship of Mansonone F, a Potent Anti-MRSA SesQuiterpenoid Quinone: Insights into Minimum Structural Requirements and SAR of C3 position
- Jung, Jong-Wha (College of Pharmacy, Seoul National University) ;
- Shin, Dong-Yun (College of Pharmacy, Seoul National University) ;
- Chae, Jung-Hyun (College of Pharmacy, Seoul National University) ;
- Hyun, Soon-Sil (College of Pharmacy, Seoul National University) ;
- Suh, Young-Ger (College of Pharmacy, Seoul National University)
- 발행 : 2003.04.01
초록
The resistances to multiple antibiotics of strains of Gram-positive Staphylococci. methicillin-resistant Staphylo coccus aureus (MRSA), are now significant clinical problem. One of the major efforts of our laboratory has been the search and design and synthesis of novel lead compound for the purpose of obtaining highly potent anti-MRSA drug. Towards this end, we have recently reported the isolation of a potent anti-MRSA drug. (omitted)
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