Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
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- Pages.231.1-231.1
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- 2003
ROLES OF NADPH OXIDASE AND COX-2 IN UVB-INDUCED MMP EXPRESSION IN HaCaT HUMAN KERATINOCYTES.
- Beak, Sung-Mok (College of Pharmacy, Yeungnam University) ;
- Jin, Da-Qing (College of Pharmacy, Yeungnam University) ;
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Kim, Jung-Ae
(College of Pharmacy, Yeungnam University)
- Published : 2003.04.01
Abstract
Ultraviolet (UV) irradiation is well known to cause human skin aging and skin cancer through activation of matrix metalloproteinases (MMPs) which are responsible for the degradation of collagen, an extracellular matrix component. However, the molecular mechanisms of UV-induced MMP expression are yet to be defined. In this study, we investigated signaling molecules involved in UV-induced MMP expression in HaCaT human keratinocytes. (omitted)
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