Proceedings of the PSK Conference (대한약학회:학술대회논문집)
- 2003.04a
- /
- Pages.229.1-229.1
- /
- 2003
The Antiproliferative Effects of Bile Acids and Their Derivatives on HT-29 Human Colon Cancer Cells
- Park, Sang-Eun (Dept. of Pharmacy, Pusan National University) ;
- Yee, Su-Bog (Dept. of Pharmacy, Pusan National University) ;
- Choi, Hye-Joung (Dept. of Pharmacy, Pusan National University) ;
- Chung, Sang-Woon (Dept. of Pharmacy, Pusan National University) ;
- Park, Hwa-Sun (Dept. of Pharmacy, Pusan National University) ;
- Yoo, Young-Hyun (Dept. of Anatomy and Cell Biology, Dong-A University College of Medicine and Institute of Medical Scienc) ;
-
Kim, Nam-Deuk
(Dept. of Pharmacy, Pusan National University)
- Published : 2003.04.01
Abstract
The anti proliferative effects of bile acids and their derivatives on HT -29 human colon cancer cells were investigated. Ursodeoxycholic acid (UDCA) and its synthetic derivatives, HS-1030 and HS-1183, and chenodeoxycholic acid (CDCA) and its synthetic derivatives, HS-1199 and HS-1200 were employed for this study. General evaluations focusing on cell cycle were conducted in HT -29 human colon adenocarcinoma cell line (p53 mutant type). (omitted)
Keywords