대한약학회:학술대회논문집 (Proceedings of the PSK Conference)
- 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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- Pages.226.2-226.2
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- 2003
Optimal culture conditions for production of Escherichia coli Adhesin protein coupled to Escherichia coli Heat Labile Enterotoxin A2B in Escherichia coli TB1.
- Lee, Yong-Hwa (College of Pharmacy, Sungkyunkwan University) ;
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Rhee, Dong-Kwon
(College of Pharmacy, Sungkyunkwan University) ;
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Pyo, Suhk-Neung
(College of Pharmacy, Sungkyunkwan University)
- 발행 : 2003.04.01
초록
The FimH subunit of type 1-fimbriated Escherichia coli has been determined as a major cause of urinary tract infection. To produce a possible vaccine antigen against urinary tract infection, the fimH gene was genetically linked to the Itxa2b gene, which was then cloned into the pMAL -p2E expression vector. The chimaeric construction of pMALfimH/Itxa2b was transformed into Escherichia coli TB1 and its N-terminal amino acid sequence was analyzed. (omitted)
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